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Pepto-Bismol was first sold in 1900 [20] by a doctor in New York. It was originally sold as a remedy for infant diarrhea by Norwich Pharmacal Company under the name "Bismosal: Mixture Cholera Infantum". [20] It was renamed Pepto-Bismol in 1919. Norwich Eaton Pharmaceuticals was acquired by Procter and Gamble in 1982. [21]
Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.
The active ingredient in Kaopectate has changed since its original creation. Originally, kaolinite was used as the adsorbent and pectin as the emollient. Attapulgite (a type of absorbent clay) replaced the kaolinite in the 1980s, but was banned by the U.S. Food and Drug Administration in a ruling made in April 2003.
Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething. A formula for paregoric from Dr. Chase's Recipes (1865): [7]
In the mid-1990s, Norwich constructed an Intermediate Potency solid dose form facility, from which the osteoporosis drug Actonel was launched. In 2001, the North Norwich plant was purchased from Procter & Gamble by Outsourcing Services Group, who revived the original Norwich Pharmaceuticals name by placing it on the sign in front of the plant ...
Bobbi Brown Shares Her Top Face-Transforming Makeup Tips for Women Over 50. Show comments. Advertisement. Advertisement. In Other News. Entertainment. Entertainment. USA TODAY.
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. [ 1 ] When a drug has a narrow therapeutic index , titration is especially important, because the range between the dose at which a drug is effective and the dose at which side effects occur is small. [ 2 ]
Just how does Pepto treat all those GI discomforts? --24.249.108.133 23:05, 31 May 2007 (UTC) The Pepto forms a coat in the stomach, getting between the stomach contents and the stomach lining. In the process, pepto allows the digestive tract to fuction as it otherwise would, clearing up the digestive problems for the person using it.
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