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Packed red blood cells; Pathogen reduction using riboflavin and UV light; Plasma frozen within 24 hours; Plasmapheresis; Platelet; Platelet transfusion; Platelet transfusion refractoriness; Platelet-poor plasma; Platelet-rich fibrin; Platelet-rich plasma; Plateletpheresis; Post-transfusion purpura; Postpartum bleeding; Prothrombin complex ...
It includes issues of blood donation, immunohematology and other laboratory testing for transfusion-transmitted diseases, management and monitoring of clinical transfusion practices, patient blood management, therapeutic apheresis, stem cell collections, cellular therapy, and coagulation. Laboratory management and understanding of state and ...
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, [1] for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or ...
Transfusion-associated graft versus host disease frequently occurs in immunodeficient patients where recipient's body failed to eliminate donor's T cells. Instead, donor's T cells attack the recipient's cells. It occurs one week after transfusion. [36] Fever, rash, diarrhoea are often associated with this type of transfusion reaction.
An example of a humanized monoclonal antibody is crizanlizumab, which treats sickle cell disease. [8] Human monoclonal antibodies are identified with the suffix "-umab". They originate from a human. [9] An example of a human monoclonal antibody is ustekinumab, which treats psoriasis. [8]
The term human blood group systems is defined by the International Society of Blood Transfusion (ISBT) as systems in the human species where cell-surface antigens—in particular, those on blood cells—are "controlled at a single gene locus or by two or more very closely linked homologous genes with little or no observable recombination between them", [1] and include the common ABO and Rh ...
Once inside the body the vector introduces the therapeutic gene into host cells, and the protein encoded by the newly inserted gene is then produced by the body's own cells. [11] This type of therapy can correct for the missing protein/enzyme in patients with lysosomal storage diseases.
Drug-induced autoimmune hemolytic anemia is a type of hemolytic anemia in which a mediated immune response triggers IgG and IgM antibody production in regards to the presence of high doses of penicillin via the hapten mechanism causing the reduction of red blood cells in the spleen. [34] Drug-induced nonautoimmune hemolytic anemia