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Omeprazole, sold under the brand names Prilosec and Losec, among others, is a medication used in the treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger–Ellison syndrome. [1] It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. [1]
In the absence of heart abnormalities, the diagnosis is often made on the basis of symptoms. A gastroenterologist will perform a colonoscopy, endoscopy, and abdominal ultrasound to locate or rule out problems in the abdomen. Determining the cause of Roemheld syndrome is still not an exact science.
Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]
deaths from causes related to cardiovascular disease by 17%. hospitalizations for heart failure by 76%. non-fatal myocardial infarction (heart attack) by 24%. the need for coronary ...
Other causes of chest pain such as heart disease should be ruled out before making the diagnosis. [42] Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or extraesophageal reflux disease (EERD).
About 13% — roughly 3,600 participants — had either a heart attack or stroke, had surgery to fix a narrowed or blocked artery, or died from heart disease over the 30-year follow-up period.
The rate of omeprazole absorption is decreased by concomitant food intake. [79] In addition, the absorption of lansoprazole and esomeprazole is decreased and delayed by food. It has been reported, however, that these pharmacokinetic effects have no significant impact on efficacy.
That can trigger an increased heart rate and blood pressure, putting more strain on the heart. “Anything that can raise your heart rate can cause heart attacks and potentially heart failure ...
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