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Prolactin (PRL), also known as lactotropin and mammotropin, is a protein best known for its role in enabling mammals to produce milk. It is influential in over 300 separate processes in various vertebrates, including humans. [5] Prolactin is secreted from the pituitary gland in response to eating, mating, estrogen treatment, ovulation and ...
Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [10] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men.
Estrogen and progesterone cause the secretion of high levels of prolactin from the anterior pituitary, [32] [33] which reach levels as high as 20 times greater than normal menstrual cycle levels. [31] IGF-1 and IGF-2 levels also increase dramatically during pregnancy, due to secretion of placental growth hormone (PGH). [34]
Estradiol is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. [1] Due to its estrogenic activity, estradiol has antigonadotropic effects and can inhibit fertility and suppress sex hormone production in both women and men.
A prolactin cell (also known as a lactotropic cell, epsilon acidophil, lactotrope, lactotroph, mammatroph, mammotroph) is a cell in the anterior pituitary which produces prolactin (a peptide hormone) in response to hormonal signals including dopamine (which is inhibitory), thyrotropin-releasing hormone and estrogen (especially during pregnancy), which are stimulatory.
The volumes of sexually dimorphic brain structures in transgender women were found to change and approximate typical female brain structures when exposed to estrogen concomitantly with androgen deprivation over a period of months, [31] suggesting that estrogen and/or androgens have a significant part to play in sex differentiation of the brain ...
Estrogen HF Tooltip Hot flashes VE Tooltip Vaginal epithelium UCa Tooltip Urinary calcium FSH Tooltip Follicle-stimulating hormone LH Tooltip Luteinizing hormone HDL Tooltip High-density lipoprotein-C Tooltip Cholesterol SHBG Tooltip Sex hormone-binding globulin CBG Tooltip Corticosteroid-binding globulin AGT Tooltip Angiotensinogen Liver ...
Estrogen promotes the development of breast cancers that have estrogen receptor (ER) by stimulating the proliferation and survival of breast cancer cells. [39] Estrogen receptor (ER) is a significant indicator for predicting outcomes and guiding treatment decisions, and it is found in around 75% of breast cancers. [ 39 ]
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