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Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication.It is commonly prescribed for balance disorders or to alleviate vertigo symptoms.It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
Betahistine is the most widely prescribed medication for the treatment of Meniere's disease. The drug is thought to increase blood flow to the inner ear and to prevent the frequency and intensity of episodes. While Betahistine is considered safe, there is insufficient evidence that it is an effective treatment. [14]
An H 3 receptor antagonist is a type of antihistaminic drug used to block the action of histamine at H 3 receptors.. Unlike the H 1 and H 2 receptors which have primarily peripheral actions, but cause sedation if they are blocked in the brain, H 3 receptors are primarily found in the brain and are inhibitory autoreceptors located on histaminergic nerve terminals, which modulate the release of ...
A histamine agonist is a drug which causes increased activity at one or more of the four histamine receptor subtypes. H 1 agonists promote wakefulness. [1] H 2: Betazole and Impromidine are examples of agonists used in diagnostics to increase histamine. H 3: Betahistine is a weak Histamine 1 agonist and a very strong antagonist of the Histamine ...
Medical treatment with anti-vertigo medications may be considered in acute, severe exacerbation of BPPV, but in most cases are not indicated. These primarily include drugs of the antihistamine and anticholinergic class, such as meclizine [9] and hyoscine butylbromide (scopolamine), respectively. The medical management of vestibular syndromes ...
Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear There is a wide range of ototoxic medications, for example, antibiotics , antimalarials , chemotherapeutic agents , non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics . [ 2 ]
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Signs of ear infection include shaking of the head, and scratching at or under the ear. Some animals may also paw the ear or try to rub it on other objects to relieve pain and discomfort. Ear infections often result in a darker red ear, dirt in the ear, or a general inflamed appearance. Chronic allergic otitis externa in a dog with atopic ...
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