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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
For example, severe hypokalaemia has been associated with distal renal tubular acidosis from laxative abuse. [26] Metabolic alkalosis is the most common acid-base imbalance observed. [ 26 ] Other significant adverse effects include rhabdomyolysis , [ 26 ] steatorrhoea , [ 26 ] inflammation and ulceration of colonic mucosa, [ 26 ] pancreatitis ...
A high volume example is sodium bis(2-ethylhexyl) sulfosuccinate. This is perhaps best known as the laxative docusate, however its main use is as a surfactant for which it finds common use in personal-care and household-care products, often under the name Aerosol-OTs. [1]
Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel. The increased water content softens the stool and stimulates the bowel to contract (move its ...
The Dietary Guidelines for Americans have been criticized for recommending a diet that contains less than 2.3 grams of sodium (5.8 grams of salt/day). Notably, 95% of the world's populations have a mean intake of salt that is between 6g and 12g daily and evidence on the health effects of salt does not support such a severe restriction on salt ...
Whole bowel irrigation with polyethylene glycol and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation. [6] Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for polyethylene glycol used as a laxative. The name may be followed by a number that ...
The diet itself seems pretty straight-forward, says Keri Gans, M.S., R.D.N., C.D.N., registered dietitian nutritionist & certified yoga teacher in New York City. “This diet was developed by ...
Like synthetic surfactants, they are composed of a hydrophilic moiety made up of amino acids, peptides, (poly)saccharides, or sugar alcohols and a hydrophobic moiety consisting of fatty acids. Correspondingly, the significant classes of biosurfactants include glycolipids , lipopeptides and lipoproteins, and polymeric surfactants as well as ...