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Rubella virus, scientific name Rubivirus rubellae, is a member of the genus Rubivirus and belongs to the family of Matonaviridae, whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid.
Rubella, also known as German measles or three-day measles, [6] is an infection caused by the rubella virus. [3] This disease is often mild, with half of people not realizing that they are infected. [ 1 ] [ 7 ] A rash may start around two weeks after exposure and last for three days. [ 1 ]
The Rubella virus 3′ cis-acting element RNA family represents a cis-acting element found at the 3′ UTR in the rubella virus. This family contains three conserved step loop structures. [ 1 ] Calreticulin (CAL), which is known to bind calcium in most eukaryotic cells, is able to specifically bind to the first stem loop of this RNA. [ 1 ]
With the introduction of the rubella vaccine in 1969, the number of cases of rubella in the United States has decreased 99%, from 57,686 cases in 1969 to 271 cases in 1999. [3] For women who plan to become pregnant, the MMR (measles mumps, rubella) vaccination is highly recommended, at least 28 days prior to conception. [ 17 ]
The 1962–1965 rubella epidemic was an outbreak of rubella across Europe and the United States. [ 1 ] [ 2 ] The Rubella virus, also known as the German measles, is a single-stranded RNA virus from the family Togaviridae and genus Rubivirus . [ 3 ]
Rubella virus 3′ cis-acting element; Ruhugu virus; S. Sense, The National Deafblind and Rubella Association This page was last edited on 6 December 2023, at 11:03 ...
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The virus is highly contagious and is spread by coughing and sneezing via close personal contact or direct contact with secretions. [52] Measles is the most contagious virus known. [20] It remains infective for up to two hours in that airspace or nearby surfaces.