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  2. COVID-19 vaccine clinical research - Wikipedia

    en.wikipedia.org/wiki/COVID-19_vaccine_clinical...

    COVID-19 vaccine clinical research uses clinical research to establish the characteristics of COVID-19 vaccines. These characteristics include efficacy , effectiveness , and safety. As of November 2022 [update] , 40 vaccines are authorized by at least one national regulatory authority for public use: [ 1 ] [ 2 ]

  3. ZF2001 - Wikipedia

    en.wikipedia.org/wiki/ZF2001

    ZF2001, trade-named Zifivax or ZF-UZ-VAC-2001, is an adjuvanted protein subunit COVID-19 vaccine developed by Anhui Zhifei Longcom in collaboration with the Institute of Microbiology at the Chinese Academy of Sciences. [2] [3] The vaccine candidate is in Phase III trials with 29,000 participants in China, Ecuador, Malaysia, Pakistan, and ...

  4. Mitochondrial biogenesis - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_biogenesis

    Mitochondrial biogenesis is the process by which cells increase mitochondrial numbers. [ 1 ] [ 2 ] It was first described by John Holloszy in the 1960s, when it was discovered that physical endurance training induced higher mitochondrial content levels, leading to greater glucose uptake by muscles. [ 3 ]

  5. Human mitochondrial genetics - Wikipedia

    en.wikipedia.org/wiki/Human_mitochondrial_genetics

    The human mitochondrial genome is the entirety of hereditary information contained in human mitochondria. Mitochondria are small structures in cells that generate energy for the cell to use, and are hence referred to as the "powerhouses" of the cell. Mitochondrial DNA (mtDNA) is not transmitted through nuclear DNA (nDNA).

  6. Corbevax - Wikipedia

    en.wikipedia.org/wiki/Corbevax

    The vaccine consists of a version of the receptor binding domain (RBD) of the SARS‑CoV‑2 spike protein, together with the adjuvants aluminium hydroxide gel and CpG 1018. [2] As the RBD protein is poorly immunogenic alone, adjuvantation is essential for a RBD-based vaccine immunogenicity. [ 9 ]

  7. Abdala (vaccine) - Wikipedia

    en.wikipedia.org/wiki/Abdala_(vaccine)

    Abdala, technical name CIGB-66, is a COVID-19 vaccine developed by the Center for Genetic Engineering and Biotechnology in Cuba. [2] This candidate, named after a patriotic drama by Cuban independence hero José Martí , is a protein subunit vaccine containing COVID-derived proteins that trigger an immune response. [ 3 ]

  8. History of COVID-19 vaccine development - Wikipedia

    en.wikipedia.org/wiki/History_of_COVID-19...

    All RMPs for COVID‑19 vaccines will be published on the EMA's website. [136] The EMA published guidance for developers of potential COVID‑19 vaccines on the clinical evidence to include in marketing authorization applications. [137] In November 2020, the CHMP started a rolling review of the Moderna vaccine for COVID‑19 known as mRNA-1273 ...

  9. Nucleoside-modified messenger RNA - Wikipedia

    en.wikipedia.org/wiki/Nucleoside-modified...

    A nucleoside-modified messenger RNA (modRNA) is a synthetic messenger RNA (mRNA) in which some nucleosides are replaced by other naturally modified nucleosides or by synthetic nucleoside analogues.

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