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A peptic ulcer is a defect in the inner lining of the stomach or duodenum typically due to excessive stomach acid. Extension of the ulcer through the lining of the digestive tract results in spillage of the stomach or intestinal contents into the abdominal cavity, leading to an acute chemical peritonitis. [13] [14] Helicobacter pylori infection ...
The cause for Valentino's syndrome is due to a perforated ulcer located in the duodenum. This occurs when ulcers that have gone untreated for long periods of time, and as a result has burned through the stomach wall. Risk factors for a perforated ulcers include bacterial infection, such as H. pylori, and routine use of nonsteroidal anti ...
A perforated ulcer can be grouped into a stercoral perforation which involves a number of different things that cause perforation of the intestine wall. The first symptom of a perforated peptic ulcer is usually sudden, severe, sharp pain in the abdomen. [1] The pain is typically at its maximum immediately and persists.
Perforation of part of the gastrointestinal tract is the most common cause of peritonitis. Examples include perforation of the distal esophagus (Boerhaave syndrome), of the stomach (peptic ulcer, gastric carcinoma), of the duodenum (peptic ulcer), of the remaining intestine (e.g., appendicitis, diverticulitis, Meckel diverticulum, inflammatory ...
The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma. A perforated appendix seldom causes a pneumoperitoneum. Spontaneous pneumoperitoneum is a rare case that is not caused by an abdominal organ rupture.
rarely, an ulcer can lead to a gastric or duodenal perforation, which leads to acute peritonitis and extreme, stabbing pain, [14] and requires immediate surgery. A history of heartburn or gastroesophageal reflux disease (GERD) and use of certain medications can raise the suspicion for peptic ulcer.
It has also been observed to cause villus ischemia, and increase intestinal motility. [15] The net result of these changes is induced diarrhoea. [15] Enteritis necroticans is an often fatal illness, caused by β-toxin of Clostridium perfringens. [16] This causes inflammation and segments of necrosis throughout the gastrointestinal tract.
Known causes of duodenitis include: [2] Helicobacter pylori infection; Coeliac disease; Bacterial infection; Viral infection; NSAIDs; Autoimmune diseases (i.e. Crohn's disease) Duodenal lymphocytosis; Idiopathic