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Meloxicam is used in veterinary medicine mainly to treat dogs, [32] [33] but also sees off-label use in other animals such as cattle and exotics. [ 34 ] [ 35 ] In the European Union and other countries it is not considered off-label and can be used in cattle, pigs, horses, dogs, cats and guinea pigs. [ 36 ]
Meloxicam is a non-steroidal anti-inflammatory drug that is approved in the U.S. for a single post-operative injection in cats. [21] As of May 2013, the FDA issued a boxed warning regarding the use of thyroid hormone stimulating agents in treatment of obesity. [22] Data does not indicate any benefits to using these agents for weight loss.
The existing nonsteroidal anti-inflammatory drugs differ in their relative specificities for COX-2 and COX-1; while aspirin and ibuprofen inhibit COX-2 and COX-1 enzymes, other NSAIDs appear to have partial COX-2 specificity, particularly meloxicam . [39] Aspirin is ≈170-fold more potent in inhibiting COX-1 than COX-2. [40]
In the United States, meloxicam is approved for use only in canines, whereas (due to concerns about liver damage) it carries warnings against its use in cats [168] [169] except for one-time use during surgery. [170] In spite of these warnings, meloxicam is frequently prescribed "off-label" for non-canine animals including cats and livestock ...
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In the European Union, the combination bupivacaine/meloxicam is indicated for treatment of somatic postoperative pain from small- to medium-sized surgical wounds in adults. [ 2 ] In the United States it is indicated for soft tissue or periarticular instillation to produce postsurgical analgesia for up to 72 hours after bunionectomy, open ...
The Prescribing Information follows one of two formats: "physician labeling rule" format or "old" (non-PLR) format. For "old" format labeling a "product title" may be listed first and may include the proprietary name (if any), the nonproprietary name, dosage form(s), and other information about the product.
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