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Nalmefene, sold under the brand name Revex among others, is a medication that is used in the treatment of opioid overdose and alcohol dependence. [2] [3] Nalmefene belongs to the class of opioid antagonists and can be taken by mouth, administered by injection, or delivered through nasal administration.
The first over-the-counter naloxone, a drug used to reverse opioid overdose, is starting to come available in retail stores and online. The medicine, with the brand name Narcan, has a suggested ...
[119] [120] CDC estimates that the US programs for drug users and their caregivers prescribing take-home doses of naloxone and training on its use prevented 10,000 opioid overdose deaths by 2014. [119] In Australia, some forms of naloxone are available "over the counter" in pharmacies free without a prescription under the Take Home Naloxone ...
Naltrexone is also a partial inverse agonist, and this property is exploited in treatment of opioid addiction, as a sustained course of low-dose naltrexone can reverse the altered homeostasis which results from long-term abuse of opioid agonist drugs. This is the only treatment available which can reverse the long-term after effects of opioid ...
The Food and Drug Administration is pushing for drugmakers to apply for over-the-counter approval for naloxone, the opioid overdose antidote. FDA opens door to make opioid overdose antidote ...
After years of continuously rising opioid overdoses, the US Centers for Disease Control and Prevention reported that overdose deaths decreased 3% in 2023, the first annual decrease since 2018. A ...
On 19 January 2018, the Los Angeles County Department of Medical Examiner said that musician Tom Petty's 2017 death was an accidental drug overdose as a result of mixing medications that included fentanyl, acetyl fentanyl, and despropionyl fentanyl (among others). He was reportedly treating "many serious ailments" that included a broken hip.
After several recent fentanyl-related overdoses, including the death of a 15-year-old girl, the Los Angeles Unified School District is providing all of its schools with a medication that can ...
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