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The average middle ear volume is 0.4 mL, which limits otic accumulation in overdose. [6] It is unlikely that an cerumenolytic administered into the ear would cause systemic toxicity in an overdose situation, due to the lack of systemic absorption resulting from minimal volume flow within the inner ear. [ 7 ]
Earwax helps protect the ear by trapping dust and other foreign particles that could filter through and damage the eardrum. [5] Normally, earwax moves toward the opening of the ear and falls out or is washed away, but sometimes excessive earwax can gather and become hard to remove. This is referred to as excessive earwax or impacted cerumen. [21]
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