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The liver damage can consist of damage to liver cells, hepatic sinusoidal syndrome (obstruction of the veins in the liver), cholestasis (where bile does not flow from the liver to the intestine) and liver fibrosis. [127] [128] Nephrotoxicity (kidney damage) can be caused by tumor lysis syndrome and also due direct effects of drug clearance by ...
Complications increase when the initial cause of the liver damage is still present. [12] Liver damage can be caused by viruses, alcohol, medications, and other hepatotoxins. [12] Acetaminophen, found in many prescription and over-the-counter medications, is the most common drug that can cause liver damage if taken in a high dose or in ...
It is classically marked by weight gain due to fluid retention, increased liver size, and raised levels of bilirubin in the blood. [1] The name sinusoidal obstruction syndrome (SOS) is preferred if hepatic veno-occlusive disease happens as a result of chemotherapy or bone marrow transplantation. [1] [2]
These methods can help reveal fatty deposits in the liver and rule out other causes of liver damage. Related: 4 Science-Backed Ways to Keep Your Liver Healthy 5 Sneaky Signs You Might Have NAFLD
Fatty liver disease happens when fat builds up in your liver. This can cause damage, inflammation, and other complications. ... For alcoholic liver disease, treatment will include cutting out alcohol.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
The most common causes of CKD are high blood pressure and diabetes, "which damage the small blood vessels and filtering units in the kidneys over time," says Nagata. Other potential causes he ...
Rates of elevated liver enzymes have ranged from 2.9 to 11.4% in these studies, which spontaneously resolved in some women and necessitated discontinuation of treatment in others. [ 138 ] [ 139 ] No cases of liver failure or death due to liver toxicity were seen with bicalutamide in the initial clinical development programme for prostate cancer ...