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Schematic showing the direct and indirect Coombs tests. The two Coombs tests are based on anti-human antibodies binding to human antibodies, commonly IgG or IgM.These anti-human antibodies are produced by plasma cells of non-human animals after immunizing them with human plasma.
Congenital rubella syndrome (CRS) occurs when a human fetus is infected with the rubella virus (German measles) via maternal-fetal transmission and develops birth defects. [1] The most common congenital defects affect the ophthalmologic, cardiac, auditory, and neurologic systems.
The water-accessible surface area of an IgG antibody. Immunoglobulin G (IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation. [1] IgG molecules are created and released by plasma B cells. Each IgG antibody has two paratopes.
The term "Rh Disease" is commonly used to refer to HDFN due to anti-D antibodies, and prior to the discovery of anti-Rh o (D) immune globulin, it was the most common type of HDFN. The disease ranges from mild to severe, and occurs in the second or subsequent pregnancies of Rh-D negative women when the biologic father is Rh-D positive.
The genome encodes several non-coding RNA structures; among them is the rubella virus 3' cis-acting element, which contains multiple stem-loops, one of which has been found to be essential for viral replication. [12] The only significant region of homology between rubella and the alphaviruses is located at the NH2 terminus of non structural ...
Rubella is seldom given as an individual vaccine and is often given in combination with measles, mumps, or varicella (chickenpox) vaccines. [19] [20] Below is the list of measles-containing vaccines: Rubella vaccine (standalone vaccine) Measles and rubella combined vaccine ; Measles, mumps and rubella combined vaccine (MMR vaccine) [21] [22] [23]
Anti-seizure medications: Gabapentin, carbamazepine, and valproic acid. Antihistamines: Diphenhydramine (the active ingredient in Benadryl) Diabetes medications: Insulin and thiazolidinediones.
Rubella, also known as German measles or three-day measles, [6] is an infection caused by the rubella virus. [3] This disease is often mild, with half of people not realizing that they are infected. [1] [7] A rash may start around two weeks after exposure and last for three days. [1] It usually starts on the face and spreads to the rest of the ...