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  2. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    granted for three indications: HER2-positive breast cancer with prior anti-HER2-based treatment; HER2 low (IHC 1+ or IHC 2+/ISH) breast cancer; and non-small cell-lung cancer with an activating HER2 mutation Dupilumab: Regeneron Pharmaceuticals: granted for two indications: eosinophilic esophagitis; and atopic dermatitis: Ivosidenib: Servier ...

  3. Tucatinib - Wikipedia

    en.wikipedia.org/wiki/Tucatinib

    Tucatinib, sold under the brand name Tukysa, is an anticancer medication used for the treatment of HER2-positive breast cancer. [3] [4] It is a small molecule inhibitor of HER2. [6] [7] It was developed by Array BioPharma and licensed to Cascadian Therapeutics (formerly Oncothyreon, subsequently part of Seattle Genetics). [8]

  4. Lapatinib - Wikipedia

    en.wikipedia.org/wiki/Lapatinib

    In March 2007, the U.S. Food and Drug Administration (FDA) approved lapatinib in combination therapy for breast cancer patients already using capecitabine (Xeloda). [4] [5] In January 2010, Tykerb received accelerated approval for the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer that overexpresses the HER2 receptor and for whom hormonal therapy is ...

  5. Drugs for advanced breast cancer could help patients with ...

    www.aol.com/drugs-advanced-breast-cancer-could...

    Researchers explored the use of the treatment for other cancers, including that of the bile ducts.

  6. New breast cancer drugs to benefit thousands - AOL

    www.aol.com/breast-cancer-drugs-benefit...

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  7. Trastuzumab - Wikipedia

    en.wikipedia.org/wiki/Trastuzumab

    Trastuzumab, sold under the brand name Herceptin among others, is a monoclonal antibody used to treat breast cancer and stomach cancer. [30] [27] [31] [32] It is specifically used for cancer that is HER2 receptor positive. [30]

  8. Pertuzumab - Wikipedia

    en.wikipedia.org/wiki/Pertuzumab

    Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...

  9. Pfizer (PFE) Q3 2024 Earnings Call Transcript - AOL

    www.aol.com/pfizer-pfe-q3-2024-earnings...

    Finally, to build on the foundation for our drugs, we are making progress with development of two candidates we believe can replace the current backbones of ER+/HER2- breast cancer.

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