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Botulinum toxin injection is commonly used for small and moderate degrees of infantile esotropia, acquired adult strabismus, and where it is a consequence of retinal detachment surgery, that is, in cases where there is good potential for binocular vision, so that the corrected alignment can be stabilized by motor fusion.
Botulinum toxin is the most acutely lethal toxin that is known. It is produced by the bacterium clostridium botulinum.It acts inside nerve terminals by decreasing the release of acetylcholine, blocking neuromuscular transmission and thereby causing flaccid muscular paralysis.
Accommodative esotropia (also called refractive esotropia) is an inward turning of the eyes due to efforts of accommodation. It is often seen in patients with moderate amounts of hyperopia . The person with hyperopia, in an attempt to "accommodate" or focus the eyes, converges the eyes as well, as convergence is associated with activation of ...
Strabismus is usually treated with a combination of eyeglasses, vision therapy, and surgery, depending on the underlying reason for the misalignment. As with other binocular vision disorders, the primary goal is comfortable, single, clear, normal binocular vision at all distances and directions of gaze.
The earliest successful strabismus surgery intervention is known to have been performed on 26 October 1839 by Johann Friedrich Dieffenbach on a 7-year-old esotropic child; a few earlier attempts had been performed in 1818 by William Gibson of Baltimore, a general surgeon and professor at the University of Maryland. [2]
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During an eye examination, the presence of suppression and the size and location of the suppression scotoma may be the Worth 4 dot test (a subjective test that is considered to be the most precise suppression test), or with other subjective tests such as the Bagolini striated lens test, or with objective tests such as the 4 prism base out test.
In the 1970s, addicts self-treated with illicit methadone because of the severe restrictions on the medication and limited access to clinics. While any illegal trade in a medication should be a concern, there is scant evidence that Suboxone is being used as a gateway to drug use in the U.S. Addicts say taking the medication just helps them feel ...