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Yohimbine (/ j oʊ ˈ h ɪ m b iː n /), [2] also known as quebrachine, is an indole alkaloid derived from the bark of the African tree Pausinystalia johimbe; also from the bark of the unrelated South American tree Aspidosperma quebracho-blanco. Yohimbine is an α 2-adrenergic receptor antagonist, and has been used in a variety of research ...
As of 2016, the International Society for the Study of the Aging Male defines late-onset hypogonadism as a series of symptoms in older adults related to testosterone deficiency that combines features of both primary and secondary hypogonadism; the European Male Aging Study (a prospective study of ~3000 men) [10] defined the condition by the presence of at least three sexual symptoms (e.g ...
[55] [56] Yohimbine is more selective to α 2 adrenoceptor; [56] by blocking presynaptic α 2-adrenoceptors, it increases the release of norepinephrine thereby raising the blood pressure. Yohimbine was used for the treatment of erectile dysfunction in men until emergence of more efficient drugs. [57] Some alkaloids affect the turnover of ...
A history of two or more prior head injuries was associated with over two times increased risk of dementia. Be physically active Studies show that being physically active can help lower your risk ...
The CDC released new COVID-19 vaccination guidelines for people 65 and up and those who are immunocompromised: Get two shots. Experts explain.
In the absence of compelling indications or contraindications, patients should take alpha blockers as a step 4 therapy to reduce blood pressure, but only if the use of ACE inhibitors, angiotensin-II receptor blockers, calcium channel blockers, or thazide diuretics (in full dose or in combinations) have not been efficacious.
As the name suggests, GrandPad is a purpose-built, all-in-one tablet and phone designed specifically for adults aged 75 and older. Actually, the average user is 85 years old, says the company.
Here are links to possibly useful sources of information about Yohimbine. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC