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An old bottle of AA Hyde Mentholatum Ointment. A.B.C. Liniment was used from approximately 1880 to 1935. [2] [3] It was named for its three primary ingredients: aconite, belladonna, and chloroform. [2] There were numerous examples of poisoning from the mixture, resulting in at least one death. [4] [5] [6] [7]
A Murphy drip apparatus [1]. A Murphy drip is a rectal infusion apparatus to administer the medical procedure of proctoclysis, also known as rectoclysis. [2] [3] During the procedure, an end of the Murphy drip is inserted into the rectum and large quantities of liquid are infused into the rectum drop by drop. [4]
The concentration in the blood or urine at particular time points can be graphed to show an area under the curve and the extent and duration of absorption and distribution to provide a measure of systemic absorption. This can be done in animals or humans with a dry chemical powder or a chemical in solution. [17]
A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Although the skin is a large and logical target for drug delivery, its basic functions limit its utility for this purpose. The skin functions mainly to protect the body from external penetration (by e.g. harmful substances and microorganisms) and to contain all body fluids.
That same month, an 88-year-old man and a 94-year-old woman in Brisbane, Australia, received four times the recommended dose of Pfizer's vaccine. They did not experience any serious adverse reactions.
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