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Hans Asperger. Asperger syndrome (AS), also known as Asperger's syndrome or Asperger's, is a term formerly used to describe a neurodevelopmental condition characterized by significant difficulties in social interaction and nonverbal communication, along with restricted, repetitive patterns of behavior and interests. [5]
Heritability of autism. The heritability of autism is the proportion of differences in expression of autism that can be explained by genetic variation; if the heritability of a condition is high, then the condition is considered to be primarily genetic. Autism has a strong genetic basis. Although the genetics of autism are complex, autism ...
Conditions comorbid to autism. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that begins in early childhood, persists throughout adulthood, and affects two crucial areas of development: social communication and restricted, repetitive patterns of behavior. [1] There are many conditions comorbid to autism spectrum disorder, such ...
Frequency. One in 100 people (1%) worldwide [ 9 ][ 10 ] Autism, also called autism spectrum disorder[ a ] (ASD), is a neurodevelopmental disorder characterized by symptoms of deficient reciprocal social communication and the presence of restricted, repetitive, and inflexible patterns of behavior. Autism generally affects a person's ability to ...
Prenatal viral infection has been called the principal non-genetic cause of autism. Prenatal exposure to rubella or cytomegalovirus activates the mother's immune response and may greatly increase the risk for autism in mice. [71] Congenital rubella syndrome is the most convincing environmental cause of autism. [72]
History of Asperger syndrome. Asperger syndrome (AS) was formerly a separate diagnosis under autism spectrum disorder. Under the DSM-5 and ICD-11, patients formerly diagnosable with Asperger syndrome are diagnosable with Autism Spectrum Disorder. The term is considered offensive by some autistic individuals. [1]
Pathophysiology of autism. The pathophysiology of autism is the study of the physiological processes that cause or are otherwise associated with autism spectrum disorders. Autism's symptoms result from maturation-related changes in various systems of the brain. [1] How autism occurs is not yet well understood.
Diagnosis of autism. The diagnosis of autism is based on a person's reported and directly observed behavior. [1] There are no known biomarkers for autism spectrum conditions that allow for a conclusive diagnosis. [2] In most cases, diagnostic criteria codified in the World Health Organization's International Classification of Diseases (ICD) or ...