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Adrenoleukodystrophy (ALD) is a disease linked to the X chromosome. It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very long chain fatty acids in tissues throughout the body.
The subdivisions of this spectrum are hyperpipecolic acidemia, infantile Refsum disease, neonatal adrenoleukodystrophy, and Zellweger syndrome. It can also be referred to as peroxisomal biogenesis disorders, Zellweger syndrome spectrum, NALD, cerebrohepatorenal syndrome, and ZSS. [ 2 ]
It is also carried in a recessive pattern. The X chromosome is a sex chromosome, and since women have two "chances" of acquiring a normal X chromosome (one maternal x, one paternal x), and males only one chance (one maternal x), this disease is more likely to be seen in males than in females. The mutation resulting in adult-onset leukodystrophy ...
Recognizing the signs of a stroke in women could make all the difference in saving a life. Here are 7 signs to look for. ... these symptoms would not improve over time. Some symptoms on the list ...
There's no magic age for retirement. One person might retire at 30, and another might continue working well into their 70s. For You: 10 Steps To Prepare For Retirement Consider This: Cutting ...
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Adrenal insufficiency is a condition in which the adrenal glands do not produce adequate amounts of steroid hormones.The adrenal glands—also referred to as the adrenal cortex—normally secrete glucocorticoids (primarily cortisol), mineralocorticoids (primarily aldosterone), and androgens.
A 2006 study in the American Journal of Psychiatry found that the ratio of adult men diagnosed with ADHD to adult women diagnosed with ADHD was about 1.6 to 1. According to experts, the breakdown ...