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Phenacetin's analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point.
The Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals, more commonly known by its abbreviation CPS, [1] is a reference book that contains drug monographs and numerous features which help healthcare professionals prescribe and use drugs safely and appropriately.
In 1989, the CDA's predecessor, the Canadian Coordinating Office for Health Technology Assessment (CCOHTA), was created by the federal government in response to this challenge. [1] [5] In 2006, the organization became the Canadian Agency for Drugs and Technologies in Health (CADTH). [3] [6]
It features original research, clinical reviews, commentaries, evidence briefs, clinical practice guidelines and practice tools relating to advancing pharmacy practice towards patient-centred care and improving outcomes. The journal has a circulation of over 18,000. It is the official publication of the Canadian Pharmacists Association. [1]
Established in 2002, the Canadian International Pharmacy Association ("CIPA") is a Canadian association of licensed pharmacy businesses offering mail order pharmacy services to Canadian and international patients. CIPA members sell pharmaceuticals and maintenance medications to individuals upon receipt of a valid prescription.
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Mental health experts warned social factors could be contributing to the rise in gender dysphoria in children, after a new study found cases have skyrocketed over a ten-year period.
In the 1950s, Spühler and Zollinger reported an association between kidney injury and the chronic use of phenacetin. [21] They noted that chronic users of phenacetin had an increased risk of developing specific kidney injuries, namely renal papillary necrosis and chronic interstitial nephritis. This condition was dubbed analgesic nephropathy ...