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Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of the brain. It has a distinctive, curved shape that has been likened to the sea-horse monster of Greek mythology and the ram's horns of Amun in Egyptian mythology .
View of left entorhinal cortex (red) from beneath the brain, with front of brain at top. Artist's rendering. The superficial layers – layers II and III – of EC project to the dentate gyrus and hippocampus: Layer II projects primarily to dentate gyrus and hippocampal region CA3; layer III projects primarily to hippocampal region CA1 and the subiculum.
CA3 has been implicated in a number of working theories on memory and hippocampal learning processes. Slow oscillatory rhythms (theta-band; 3–8 Hz) are cholinergically driven patterns that depend on coupling of interneurons and pyramidal cell axons via gap junctions, as well as glutaminergic (excitatory) and GABAergic (inhibitory) synapses.
The hippocampus is located in the allocortex, with neural projections into the neocortex, in humans [1] [2] [3] as well as other primates. [4] The hippocampus, as the medial pallium, is a structure found in all vertebrates. [5] In humans, it contains two main interlocking parts: the hippocampus proper (also called Ammon's horn), and the dentate ...
The subiculum (Latin for "support") is the most inferior component of the hippocampal formation. It lies between the entorhinal cortex and the CA1 subfield of the hippocampus proper . The subicular complex comprises a set of related structures including (as well as subiculum proper) prosubiculum, presubiculum, postsubiculum and parasubiculum.
On rare occasion, infarcts in the hippocampus or thalamus are the cause of dementia. [12] A history of stroke increases the risk of developing dementia by around 70%, and recent stroke increases the risk by around 120%. [13] Brain vascular lesions can also be the result of diffuse cerebrovascular disease, such as small vessel disease. [5]
The dentate gyrus (DG) is part of the hippocampal formation in the temporal lobe of the brain, which also includes the hippocampus and the subiculum.The dentate gyrus is part of the hippocampal trisynaptic circuit and is thought to contribute to the formation of new episodic memories, [1] [2] the spontaneous exploration of novel environments [2] and other functions.
Lacunar strokes may result from carotid artery pathology or microemboli from the heart as in atrial fibrillation. Patients often recover well, but if there is enough white matter disease from lacunar pathology, one can see a subcortical dementia such as Binswanger disease.
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