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While antidepressants are largely effective at treating major depressive disorder (MDD), not all people experience improvements after they start taking an antidepressant.
Last but certainly not least, some tricyclic antidepressants (TCAs) are used to treat anxiety disorders. Tricyclics are also an older class of antidepressants first developed in the 1950s.
“And that — for reasons that are, frankly, poorly understood — helps many people do better with their mood and anxiety,” Humphreys said. Antidepressants don’t give people that reward or ...
Antidepressants, including SSRIs, can cross the placenta and have the potential to affect the fetus and newborn, including an increased chance of miscarriage, presenting a dilemma for pregnant women to decide whether to continue to take antidepressants at all, or if they do, considering if tapering and discontinuing during pregnancy could have ...
Ketamine’s antidepressant effects are part of what prompted researchers to explore other drugs that target glutamate—like the venerable cough suppressant dextromethorphan found in Robitussin ...
Half of these prescriptions were for depression and 16% for anxiety, the latter not being licensed for treatment with antidepressants. [42] [298] Among the suggested possible reasons why GPs are not following the guidelines are the difficulties of accessing talking therapies, long waiting lists, and the urgency of treatment.
Increasing the dosage of an antidepressant is a common strategy to treat depression that does not respond after adequate treatment duration. Practitioners who use this strategy will usually increase the dose until the person reports intolerable side effects , symptoms are eliminated, or the dose is increased to the limit of what is considered safe.
Most of the weight gain caused by antidepressants is mild, with a 2017 study from Australia finding that high-dosage antidepressant users gain 0.28kg (about 0.6 lbs) per year on average.
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