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d'Hérelle was a self-taught microbiologist. In 1917 he discovered that "an invisible antagonist", when added to bacteria on agar, would produce areas of dead bacteria. The antagonist, now known to be a bacteriophage, could pass through a Chamberland filter. He accurately diluted a suspension of these viruses and discovered that the highest ...
Bacteriophage genomes can be highly mosaic, i.e. the genome of many phage species appear to be composed of numerous individual modules. These modules may be found in other phage species in different arrangements. Mycobacteriophages, bacteriophages with mycobacterial hosts, have provided excellent examples of this mosaicism.
The first human virus to be identified was the yellow fever virus. [6] In 1881, Carlos Finlay (1833–1915), a Cuban physician, first conducted and published research that indicated that mosquitoes were carrying the cause of yellow fever, [ 7 ] a theory proved in 1900 by commission headed by Walter Reed (1851–1902).
The human phageome is thought to be brought about in newborns through prophage induction of bacteria passed on from the mother vaginally during birth. [12] However, phages can be introduced through breastfeeding, made evident through studies finding near-exact matches of crAssphage sequences between mother and child. [ 12 ]
Bacteriophage Lambda Structure at Atomic Resolution [1] Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. [2]
[32] [33] A summary of these publications was published in English in 2009 in "A Literature Review of the Practical Application of Bacteriophage Research". [34] There is an extensive library and research center at the George Eliava Institute in Tbilisi, Georgia. Phage therapy is today a widespread form of treatment in that region. [25] [24]
Mycobacteriophage Bxb1 Structure [1]. A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, [2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental ...
[8] [9] In 2014, geneticist Anna-Sapfo Malaspinas of the Center for GeoGenetics at the University of Copenhagen published a study in Current Biology that found human genetic evidence of contact between the populations of Easter Island and South America, dating to approximately 600 years ago (i.e. 1400 CE ± 100 years). [10]