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The reaction is also seen in the other diseases caused by spirochetes: Lyme disease, relapsing fever, and leptospirosis. [4] There have been case reports of the Jarisch–Herxheimer reaction accompanying treatment of other infections, including Q fever, bartonellosis, brucellosis, trichinellosis, and African trypanosomiasis. [3]
The antibiotic doxycycline is effective in preventing leptospirosis infection. [7] Human vaccines are of limited usefulness; [15] vaccines for other animals are more widely available. [16] Treatment when infected is with antibiotics such as doxycycline, penicillin, or ceftriaxone. [8] The overall risk of death is 5–10%. [10]
Leptospirosis is treated with the antibiotics doxycycline and penicillin. [28] There are more than 200 diverse pathogenic Leptospira serovars, making it challenging to develop an effective vaccine. [31] However, vaccines for the serovars known as Hardjo, Pomona, Canicola, Grippotyphosa and icterohaemorrhagiae have been developed.
Doxycycline is less likely than other antibiotic drugs to cause Clostridioides difficile colitis. [75] An erythematous rash in sun-exposed parts of the body has been reported to occur in 7.3–21.2% of persons taking doxycycline for malaria prophylaxis. One study examined the tolerability of various malaria prophylactic regimens and found ...
Doxycycline is a class of medications typically used to treat bacterial STIs after someone has been infected — a method called post-exposure prophylaxis. However, recent research suggests that ...
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
Post-exposure prophylaxis, also known as post-exposure prevention (PEP), is any preventive medical treatment started after exposure to a pathogen in order to prevent the infection from occurring. It should be contrasted with pre-exposure prophylaxis , which is used before the patient has been exposed to the infective agent.
Vaccine-preventable deaths are usually caused by a failure to obtain the vaccine in a timely manner. This may be due to financial constraints or to lack of access to the vaccine. A vaccine that is generally recommended may be medically inappropriate for a small number of people due to severe allergies or a damaged immune system. In addition, a ...
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