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Aciclovir, also known as acyclovir, [4] is an antiviral medication. [5] It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. [6] Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein–Barr virus infection.
The second dose, if given, should occur at least one to three months later. [10] The second dose, if given, provides the additional benefit of improved protection against all varicella. [44] This vaccine is a shot given subcutaneously (under the skin). It is recommended for all children under 13 and for everyone 13 or older who has never had ...
Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 Amantadine: Influenza: Influenza A virus M2 proton channel antagonist Ampligen: Avian Influenza: Immunomodulatory double-stranded RNA: Amprenavir (Agenerase) HIV Protease ...
Varicella zoster virus (VZV), also known as human herpesvirus 3 (HHV-3, HHV3) or Human alphaherpesvirus 3 (taxonomically), is one of nine known herpes viruses that can infect humans. It causes chickenpox (varicella) commonly affecting children and young adults, and shingles (herpes zoster) in adults but rarely in children.
The varicella vaccine is recommended in many countries. [12] Some countries require the varicella vaccination or an exemption before entering elementary school. A second dose is recommended five years after the initial immunization. [45] A vaccinated person is likely to have a milder case of chickenpox if they become infected. [46]
Shingrix is a suspension for intramuscular injection consisting of a lyophilized recombinant varicella zoster virus glycoprotein E antigen that is reconstituted at the time of use with AS01 B suspension as an immunological adjuvant. The antigen is a purified truncated form of the glycoprotein, expressed in Chinese hamster ovary cells.
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[1] [2] [3] Acyclovir was the first antiviral drug to get rapid approval from the FDA, and it was Corey's studies that defined its use in genital herpes. These studies led to the licensure for acyclovir in a wide variety of infections such as HSV-1, HSV-2 and varicella chickenpox virus, including the first use of an antiviral for daily long ...
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