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Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. [1]
Stroke is the third leading cause of death around the world, according to a November 2018 study, causing around 5.5 million deaths annually. “A stroke occurs when the central nervous system is ...
Cerebral infarction, also known as an ischemic stroke, is the pathologic process that results in an area of necrotic tissue in the brain (cerebral infarct). [1] In mid to high income countries, a stroke is the main reason for disability among people and the 2nd cause of death. [2]
However, many patients who were eligible for treatment were not treated. [14] [15] tPA has also been given to patients with acute ischemic stroke above age 90 years old. Although a small fraction of patients 90 years and above treated with tPA for acute ischemic stroke recover, most patients have a poor 30-day functional outcome or die. [16]
Between 1990 and 2010 the incidence of stroke decreased by approximately 10% in the developed world and increased by 10% in the developing world. [19] Overall, two-thirds of stroke occurred in those over 65 years old. [19] South Asians are at particularly high risk of stroke, accounting for 40% of global stroke deaths. [243]
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For spontaneous intracerebral hemorrhage seen on CT scan, the death rate is 34–50% by 30 days after the injury, [22] and half of the deaths occur in the first 2 days. [51] Even though the majority of deaths occur in the first few days after ICH, survivors have a long-term excess mortality rate of 27% compared to the general population. [ 52 ]
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