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Gradual (chronic) occurrences are typically caused by fungi, commonly Candida albicans. [2] [3] [4] Risk factors for paronychia include frequent hand washing and trauma to the cuticle, such as from chronic nail biting or hangnails. [2] Treatment typically involves antibiotics for bacterial infections and antifungals for fungal infections.
It can be effective in treating chronic paronychia. The preferred treatment of tinea infections is therefore clotrimazole monotherapy. [11] Topical clotrimazole cream, when combined with mechanical reduction of the nail, has been demonstrated to be effective in the treatment of onychomycosis - a fungal infection of the fingernails and toenails ...
Tacrolimus, sold under the brand name Prograf among others, is an immunosuppressive drug. After allogenic organ transplant, the risk of organ rejection is moderate. To lower the risk of organ rejection, tacrolimus is given. The drug can also be sold as a topical medication in the treatment of T cell-mediated diseases such as eczema and psoriasis.
In especially acute and severe cases, systemic steroids can be taken orally; [15] the immunosuppressive drug tacrolimus, or PUVA therapy may also be tried. [7] [8] Dapsone (diamino-diphenyl sulfone), an antibacterial, has been recommended for the treatment of dyshidrosis in some chronic cases. [21]
Although it is a structural analogue of tacrolimus, it acts somewhat differently and has different side-effects. Contrary to ciclosporin and tacrolimus, drugs that affect the first phase of T lymphocyte activation, sirolimus affects the second phase, namely signal transduction and lymphocyte clonal proliferation.
Seoul (Reuters) -Investigators found bird feathers and blood in both engines of the Jeju Air jet that crashed in South Korea last month, killing 179 people, a person familiar with the probe told ...
It is frequently associated with an internal disorder, trauma, infection, nail fungi, allergy to nail enhancement products, or side effects of drugs. Onychomadesis is the separation and falling off of a nail from the nail bed. Common causes include localized infection, minor injury to the matrix bed, or severe systemic illness.
An ingrown nail, also known as onychocryptosis (from Greek: ὄνυξ (onyx) 'nail' and κρυπτός (kryptos) 'hidden') is a common form of nail disease.It is an often painful condition in which the nail grows so that it cuts into one or both sides of the paronychium or nail bed.
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