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Hyperalgesia (/ ˌ h aɪ p ər æ l ˈ dʒ iː z i ə / or /-s i ə /; hyper from Greek ὑπέρ (huper) 'over' + -algesia from Greek ἄλγος (algos) 'pain') is an abnormally increased sensitivity to pain, which may be caused by damage to nociceptors or peripheral nerves and can cause hypersensitivity to stimulus.
Increased touch sensitivity is referred to as "tactile hyperesthesia", and increased sound sensitivity is called "auditory hyperesthesia". In the context of pain, hyperaesthesia can refer to an increase in sensitivity where there is both allodynia and hyperalgesia .
Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen. [ 1 ] [ 2 ] It is an abnormality in the immune system that causes immune diseases including allergies and autoimmunity .
Dysesthesia is an unpleasant, abnormal sense of touch. Its etymology comes from the Greek word "dys," meaning "bad," and "aesthesis," which means "sensation" (abnormal sensation). It often presents as pain [1] but may also present as an inappropriate, but not discomforting
Central pain syndrome, also known as central neuropathic pain, [1] is a neurological condition consisting of constant moderate to severe pain due to damage to the central nervous system (CNS) which causes a sensitization of the pain system. [2] [3] The extent of pain and the areas affected are related to the cause of the injury. [4]
People with fibromyalgia are hypersensitive to intense stimuli such as bright lights, loud noises, perfumes, and cold temperatures; people with the condition also have hyper-excitable nociceptors. [29] When people with fibromyalgia are subjected to intense stimuli, they experience sensory overload in the form of pain.
Sensory processing sensitivity (SPS) is a temperamental or personality trait involving "an increased sensitivity of the central nervous system and a deeper cognitive processing of physical, social, and emotional stimuli". [2]
The somatosensory system, or somatic sensory system is a subset of the sensory nervous system. It has two subdivisions, one for the detection of mechanosensory information related to touch, and the other for the nociception detection of pain and temperature. [ 1 ]