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Preparation of serum cups for a lipids panel designed to test cholesterol levels in a patient's blood. Serum (/ ˈ s ɪər ə m /) is the fluid and solvent component of blood which does not play a role in clotting. [1] It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed.
Plasma and serum are both derived from full blood, but serum is obtained by removing blood cells, fibrin clots, and other coagulation factors while plasma is obtained by only removing blood cells. [22] Blood plasma and blood serum are often used in blood tests. Tests can be done on plasma, serum or both. [23]
A low serum osmolality will suppress the release of ADH, resulting in decreased water reabsorption and more concentrated plasma. Syndrome of inappropriate ADH secretion occurs when excessive release of antidiuretic hormone results in inappropriately elevated urine osmolality (>100 mOsmol/L) relative to the blood plasma, leading to hyponatraemia.
A second vial is also sent to the laboratory. This vial is put in an instrument that measures the freezing point depression of all the solutes in the plasma. This measurement gives the true plasma osmolality. The calculated osmolality is then subtracted from the measured osmolality to provide the osmol gap, or the difference between these two ...
Understand the different processes before you decide to give.
Serum protein electrophoresis (SPEP or SPE) is a laboratory test that examines specific proteins in the blood called globulins. [1] The most common indications for a serum protein electrophoresis test are to diagnose or monitor multiple myeloma , a monoclonal gammopathy of uncertain significance (MGUS), or further investigate a discrepancy ...
Blood serum and blood plasma are similar, but serum does not contain any clotting factors such as fibrinogen, prothrombin, thromboplastin and many others. Serum includes all proteins not used in coagulation (clotting) and all the electrolytes, antibodies, antigens, hormones and any exogenous substances, such as drugs and microorganisms.
Plasma proteins are separated by using the inherent differences of each protein. Fractionation involves changing the conditions of the pooled plasma (e.g., the temperature or the acidity) so that proteins that are normally dissolved in the plasma fluid become insoluble, forming large clumps, called precipitate.
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