Search results
Results from the WOW.Com Content Network
Although initial infections with VZV during pregnancy, causing chickenpox, may lead to infection of the fetus and complications in the newborn, chronic infection or reactivation in shingles are not associated with fetal infection. [72] [73] There is a slightly increased risk of developing cancer after a shingles episode.
Shingles is caused by varicella zoster virus (VZV), an alpha-herpesvirus. Initial VZV infection usually occurs in childhood causing chickenpox. After this resolves, the virus is not eliminated from the body, but remains latent in the nerve cell bodies of the dorsal root or trigeminal ganglia, without causing symptoms.
The dorsal root ganglion is not separated by a blood brain barrier as it contains fenestrated capillaries which are highly permeable. This allows antibodies, T-cells, toxins and other substances to enter, causing damage to the nerve cell bodies. [2] Paraneoplastic sensory neuropathy occurs in the setting of cancer and is thought to involve anti ...
A dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion [1]) is a cluster of neurons (a ganglion) in a dorsal root of a spinal nerve. The cell bodies of sensory neurons known as first-order neurons are located in the dorsal root ganglia. [2] The axons of dorsal root ganglion neurons are known as afferents.
Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). Typically, the nerve pain (neuralgia) is confined to an area of skin innervated by a single sensory nerve, which is known as a dermatome. PHN is ...
What it looks like: Athlete’s foot is a rash caused by a fungal infection of the skin. People typically develop a rash between the toes, and the skin becomes white, moist, and falls apart ...
A dorsal root ganglion (DRG) from a chicken embryo (around stage of day 7) after incubation overnight in NGF growth medium stained with anti-neurofilament antibody. Note the axons growing out of the ganglion. A ganglion (pl.: ganglia) is a group of neuron cell bodies in the peripheral nervous system.
Similar to the herpes simplex viruses, after primary infection with VZV (chickenpox), the virus lies dormant in neurons, including the cranial nerve ganglia, dorsal root ganglia, and autonomic ganglia. Many years after the person has recovered from initial chickenpox infection, VZV can reactivate to cause shingles. [4]