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Increased concentrations of nortriptyline may increase the risk for side effects, including anticholinergic and nervous system adverse effects, while decreased concentrations may reduce the drug's efficacy. [39] [40] [41] Individuals can be categorized into different types of CYP2D6 metabolizers depending on which genetic variations they carry ...
The nortriptyline group experienced moderate weight gain. ... SSRI side effects include nausea, dry mouth, upset stomach, intimate dysfunction, insomnia and weight gain or loss.
Many side effects may be related to the antimuscarinic properties of the TCAs. Such side effects are relatively common and may include dry mouth, dry nose, blurry vision, lowered gastrointestinal motility or constipation, urinary retention, cognitive and/or memory impairment, and increased body temperature.
Most are non-toxic at less than 5 mg/kg except for desipramine, nortriptyline, and trimipramine, which are generally non-toxic at less than 2.5 mg/kg. [5] [2] In small children one or two pills can be fatal. [6] An electrocardiogram (ECG) should be included in the assessment when there is concern of an overdose. [2]
This study only followed participants for up to 2 years, so more research could examine the long-term effects. Future research can include randomized controlled trials and see if there are similar ...
Some people experience short-term depression following a specific life event (like losing a job or the death of a loved one) and for others, the mental health condition lasts years ...
According to a study done by the National Institute of Mental Health, medication, either alone or combined with behavioral therapy was the most effective course of treatment in reducing ADHD symptoms. They also found that although medication had some long-term side effects, it was ultimately safer and more effective than routine community care.
For example, another study published in the International Journal of Neuropsychopharmacology in 2011 compared the effects of escitalopram and nortriptyline, a tricyclic antidepressant, on the body ...
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