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Increased concentrations of nortriptyline may increase the risk for side effects, including anticholinergic and nervous system adverse effects, while decreased concentrations may reduce the drug's efficacy. [39] [40] [41] Individuals can be categorized into different types of CYP2D6 metabolizers depending on which genetic variations they carry ...
In adolescents and people over age 60, therapy should be initiated at a dose of 5 mg three times a day and increased under the supervision of a physician as needed. [5] Patients over age 60 who are taking daily doses of 20 mg or more should be closely monitored for side effects such as rapid heart rate and urinary retention. [5]
Tricyclics have a narrow therapeutic index, i.e., the therapeutic dose is close to the toxic dose. [7] Factors that increase the risk of toxicity include advancing age, cardiac status, and concomitant use of other drugs. [8] However, serum drug levels are not useful for evaluating risk of arrhythmia or seizure in tricyclic overdose. [9]
Most of the adverse effects of Wellbutrin are mild and transient, although a small percentage of people who use this medication experience more severe or longer-lasting side effects. Common side ...
If your Wellbutrin dosage is increased, you may experience more of the common side effects of bupropion, such as nausea, dizziness, abdominal pain, constipation, weight gain, trouble sleeping, dry ...
For some antidepressant users though, common side effects can ruin one of the happiest and most fulfilling parts of lives: intimacy. ... They may adjust your dosage of Zoloft, or switch you to a ...
Sometimes, people stop taking antidepressant medications due to side effects, although these effects often become less severe over time. [29] Suddenly stopping a treatment or missing several doses may cause withdrawal-like symptoms. [7]
Here are links to possibly useful sources of information about Nortriptyline. PubMed provides review articles from the past five years (limit to free review articles ) The TRIP database provides clinical publications about evidence-based medicine .