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  2. Bupivacaine - Wikipedia

    en.wikipedia.org/wiki/Bupivacaine

    Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease sensation in a specific small area. [5] In nerve blocks , it is injected around a nerve that supplies the area, or into the spinal canal's epidural space . [ 5 ]

  3. Levobupivacaine - Wikipedia

    en.wikipedia.org/wiki/Levobupivacaine

    Levobupivacaine, the S(-)-enantiomer of bupivacaine has been developed as an alternative to the racemic mixture, as it has been shown to have a lower cardiotoxicity than bupivacaine. Under European Union advice, it can be applied for minor and major surgical anaesthesia , as well as (post-operative) pain management . [ 7 ]

  4. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.

  5. Physiologically based pharmacokinetic modelling - Wikipedia

    en.wikipedia.org/wiki/Physiologically_based...

    Individuals: e.g., from males to females, from adults to children, from non-pregnant women to pregnant; From in vitro to in vivo. [14] Some of these extrapolations are "parametric" : only changes in input or parameter values are needed to achieve the extrapolation (this is usually the case for dose and time extrapolations).

  6. Ropivacaine - Wikipedia

    en.wikipedia.org/wiki/Ropivacaine

    However, new data suggested both ropivacaine (1.2-1.8 mg/kg in 40ml) and levobupivacaine (40 ml of 0.125% solution) can be used, because they have less cardiovascular and central nervous system toxicity than racemic bupivacaine.

  7. She grew up in an Arizona church community. Now, she ... - AOL

    www.aol.com/she-grew-arizona-church-community...

    Brooke Walker grew up in an Arizona church community. Families, side by side, in communion with God and each other. But the church, she says, was actually a cult. Walker spent her formative years ...

  8. From frozen waffles to onions: How recent recalls highlight ...

    www.aol.com/frozen-waffles-onions-recent-recalls...

    From E. coli traced to slivered onions on McDonald's Quarter Pounders to mass recalls of frozen waffles due to listeria risk, foodborne illness seems ever-present in the headlines.

  9. Explainer-How quickly can Trump's Musk-led efficiency panel ...

    www.aol.com/news/explainer-quickly-trumps-musk...

    The Pioneer Woman’s comfort food copycat is so much better than the original. Food. Serious Eats. Stop tossing the one ingredient that'll make your cooking even more delicious. Lighter Side.