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The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
A failure to correctly regulate these processes leads to skin disorders developing. [4] Cells of the stratum corneum contain a dense network of keratin, a protein that helps keep the skin hydrated by preventing water evaporation. These cells can also absorb water, further aiding in hydration. In addition, this layer is responsible for the ...
It forms the outermost layer of the skin and the inner lining of the mouth, esophagus and vagina. [2] In the epidermis of skin in mammals, reptiles, and birds, the layer of keratin in the outer layer of the stratified squamous epithelial surface is named the stratum corneum. Stratum corneum is made up of squamous cells which are keratinized and ...
Skin's outermost layer, known colloquially as "the barrier," is responsible for keeping pathogens out and moisture in, and those suffering from inflammatory skin conditions already have a ...
As they are water-soluble themselves, excessive water contact may leach them and inhibit their normal functions which is why prolonged contact with water makes the skin drier. [14] The intercellular lipid layer helps prevent the loss of natural moisturizing factor by sealing the outside of each corneocyte.
This keratinized layer of skin is responsible for keeping water in the body and keeping other harmful chemicals and pathogens out, making skin a natural barrier to infection. [ 7 ] 2D projection of a 3D OCT -tomogram of the skin at the fingertip, depicting the stratum corneum (≈500 μm thick) with the stratum disjunctum on top and the stratum ...
Skin sloughing is the process of shedding dead surface cells from the skin. It is most associated with cosmetic skin maintenance via exfoliation , but can also occur biologically or for medical reasons.
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]