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Factor V Leiden (rs6025 or F5 p.R506Q [1]) is a variant (mutated form) of human factor V (one of several substances that helps blood clot), which causes an increase in blood clotting (hypercoagulability).
Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. [5] In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor . [ 5 ]
Factor V Leiden is an inherited blood clotting disorder. It can cause life-threatening clots in the body and complications during pregnancy.
Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). [ 1 ] [ 2 ] Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not ...
Acquired risk factors include the strong risk factor of older age, [5] which alters blood composition to favor clotting. [59] Previous VTE, particularly unprovoked VTE, is a strong risk factor. [60] A leftover clot from a prior DVT increases the risk of a subsequent DVT. [61]
To raise awareness about a blood test that can detect that very same disorder.In an interview with People, the 35-year-old singer revealed that, months after the loss of Rosie, who was "born ...
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