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  2. Gastric glands - Wikipedia

    en.wikipedia.org/wiki/Gastric_glands

    The secretions of the different exocrine gastric gland cells produce a watery, acidic fluid into the stomach lumen called gastric juice. [5] [6] Gastric juice contains water, hydrochloric acid, intrinsic factor, pepsinogen, and salts. Adults produce around two to three litres of gastric juice per day. [5]

  3. Gastrointestinal physiology - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_physiology

    H + is pumped into the stomach by exchanging it with K +. This process also requires ATP as a source of energy; however, Cl − then follows the positive charge in the H + through an open apical channel protein. HCO 3 − secretion occurs to neutralize the acid secretions that make their way into the duodenum of the small intestine.

  4. Parietal cell - Wikipedia

    en.wikipedia.org/wiki/Parietal_cell

    These receptors are present on basolateral side of membrane. Increased cAMP level results in increased protein kinase A. Protein kinase A phosphorylates proteins involved in the transport of H + /K +-ATPase from the cytoplasm to the cell membrane. This causes resorption of K + ions and secretion of H + ions. The pH of the secreted fluid can ...

  5. Gastric acid - Wikipedia

    en.wikipedia.org/wiki/Gastric_acid

    The lowest pH of the secreted acid is 0.8, [5] but the acid is diluted in the stomach lumen to a pH of between 1 and 3. There is a small continuous basal secretion of gastric acid between meals of usually less than 10 mEq/hour. [6] There are three phases in the secretion of gastric acid which increase the secretion rate in order to digest a ...

  6. Human digestive system - Wikipedia

    en.wikipedia.org/wiki/Human_digestive_system

    The churning motion of the stomach was described among other findings. [53] In the 19th century, it was accepted that chemical processes were involved in the process of digestion. Physiological research into secretion and the gastrointestinal tract was pursued with experiments undertaken by Claude Bernard, Rudolph Heidenhain and Ivan Pavlov.

  7. Gastrointestinal wall - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_wall

    Secretion of the hormone glucose-dependent insulinotropic peptide, which stimulates the release of insulin M cells: Intestinal glands of duodenum and jejunum: Secretion of the hormone motilin, which accelerates gastric emptying, stimulates intestinal peristalsis, and stimulates the production of pepsin S cells: Intestinal glands

  8. Gastrointestinal hormone - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_hormone

    Affects gut motility; increases jejunal and ileal fluid secretion Pancreatic polypeptide: Pancreas: Inhibits pancreatic and biliary secretion Peptide YY: Colon: Inhibits food intake Somatostatin: Stomach, pancreas: Inhibits secretion and action of many hormones Substance P: Enteric nerves: Unclear Trefoil peptides: Stomach, intestine: Mucosal ...

  9. Gastric chief cell - Wikipedia

    en.wikipedia.org/wiki/Gastric_chief_cell

    It is the cell responsible for secretion of chymosin (rennin) in ruminant animals and some other animals. [1] The cell stains basophilic upon H&E staining due to the large proportion of rough endoplasmic reticulum in its cytoplasm. Gastric chief cells are generally located deep in the mucosal layer of the stomach lining, in the fundus and body ...