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The fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase was approved for medical use in the United States in June 2020. [5] [10]The FDA's approval was based on the results of a non-inferiority study in participants with HER2-positive early breast cancer, which demonstrated the fixed-dose combination of pertuzumab, trastuzumab, and hyaluronidase had comparable efficacy and ...
"Trastuzumab". Drug Information Portal. U.S. National Library of Medicine. "Hyaluronidase". Drug Information Portal. U.S. National Library of Medicine. "Trastuzumab and Hyaluronidase-oysk". National Cancer Institute. 14 March 2019. "Trastuzumab and Hyaluronidase-oysk". NCI Drug Dictionary. National Cancer Institute.
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Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...
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A decades-old cosmetic procedure called mesotherapy, which involves injecting unregulated mixtures of vitamins and drugs under the skin to reduce under-eye bags, is regaining popularity in the US.
A cleaning company has been fined $171,000 after federal investigators found 11 children working a "dangerous" overnight shift at a meat processing plant in Iowa. The U.S. Labor Department sa id ...
Wendy Williams' health has taken a turn for the worse amid her battle with dementia and aphasia. The former "Wendy Williams Show" host, 60, has become "cognitively impaired and permanently ...