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In modern times, depression, more often severe cases, is more noted as an absence of pleasure, with feelings of emptiness and flatness. [4] In the United States and Canada, the costs associated with major depression are comparable to those related to heart disease, diabetes, and back problems and are greater than the costs of hypertension. [5]
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
However, it has been found that some of the cognitive symptoms associated with pseudodementia can persist as residual symptoms and even transform into true neurodegenerative dementia in some cases. [3] Psychiatric conditions, mainly depression, is the strongest risk factor of pseudodementia rather than age.
People with psychotic depression experience the symptoms of a major depressive episode, along with one or more psychotic symptoms, including delusions and/or hallucinations. [2] Delusions can be classified as mood congruent or incongruent, depending on whether or not the nature of the delusions is in keeping with the individual's mood state. [ 2 ]
Dysthymia (/ d ɪ s ˈ θ aɪ m i É™ / dihs-THIY-mee-uh), also known as persistent depressive disorder (PDD), [3] is a mental and behavioral disorder, [5] specifically a disorder primarily of mood, consisting of similar cognitive and physical problems as major depressive disorder, but with longer-lasting symptoms.
However, most antidepressant treatments do not directly enhance DA neurotransmission, which may contribute to residual symptoms, including impaired motivation, concentration, and pleasure. [ 21 ] Preclinical and clinical research indicates that drugs inhibiting the reuptake of all three of these neurotransmitters can produce a more rapid onset ...
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