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Viruses are the most abundant biological entities on Earth, but challenges in detecting, isolating, and classifying unknown viruses have prevented exhaustive surveys of the global virome. [25] Over 5 Tb of metagenomic sequence data were used from 3,042 geographically diverse samples to assess the global distribution, phylogenetic diversity, and ...
Serratus is a large scale viroinformatics platform for uncovering the total genetic diversity of Earth's virome.Originating with the goal of uncovering novel coronaviruses [1] that may have been incidentally sequenced by other researchers, the project expanded to encompass all RNA viruses, those which encode a viral RNA-dependent RNA polymerase (RdRp).
Some of Kyrpides's recent research in microbiome data science include the exploration of Earth’s virome, [25] [26] the identification of new bacterial phyla [27] the prediction of novel folds using metagenomic sequences, [28] and the discovery and characterization of new protein families from microbiome data. [29]
One such surveillance program is the Global Virome Project (GVP) an international collaborative research initiative based at the One Health Institute at the University of California, Davis. [ 29 ] [ 30 ] The GVP aims to boost infectious disease surveillance around the globe by using low cost sequencing methods in high risk countries to prevent ...
The Global Virome Project (GVP) is an American-led international collaborative research initiative based at the One Health Institute at the University of California, Davis. [ 1 ] [ 2 ] The project was co-launched by EcoHealth Alliance president Peter Daszak , Nathan Wolfe and Edward Rubin of Metabiota , and former Chinese Center for Disease ...
Virosphere (virus diversity, virus world, global virosphere) was coined to refer to all those places in which viruses are found or which are affected by viruses. [1] [2] However, more recently virosphere has also been used to refer to the pool of viruses that occurs in all hosts and all environments, [3] as well as viruses associated with specific types of hosts (prokaryotic virosphere, [4 ...
Earth’s inner core, a red-hot ball of iron 1,800 miles below our feet, stopped spinning recently, and it may now be reversing directions, according to an analysis of seismic activity.
Sequences that are believed to be derived from unknown microbes are referred to as the microbial dark matter, [18] the dark virome, [19] or dark matter fungi. [20] Such sequences are not rare. It has been estimated that in material from humans, between 40 and 90% of viral sequences are from dark matter.