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Levothyroxine is a frequently prescribed drug in the United States, particularly for older people, as lower thyroid function can be associated with aging. ... as side effects can cause problems ...
To understand how high levels of thyroxine can be toxic and lead to thyrotoxic myopathy physiologically, consider basic neuromuscular junction function. Under normal circumstances, muscle contraction occurs when electrical impulses travel down descending axons from the brain or spinal cord towards the neuromuscular junction .
Levothyroxine has a half-life of 7.5 days when taken daily, so about six weeks is required for it to reach a steady level in the blood. [5] Side effects from excessive doses include weight loss, trouble tolerating heat, sweating, anxiety, trouble sleeping, tremor, and fast heart rate. [5]
Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, heat intolerance, diarrhea, enlargement of the thyroid, hand tremor, and weight loss. [1] Symptoms are typically less severe in the elderly and during pregnancy. [1]
Even before perimenopause, hormones naturally fluctuate with your cycle and may be different from cycle to cycle, so Dr. Rosser doesn’t put too much stock in hormone testing for this purpose.
[11] [36] Hypothyroidism affects 3-10% percent of adults, with a higher incidence in women and the elderly. [37] [38] [39] An estimated one-third of the world's population currently lives in areas of low dietary iodine levels. In regions of severe iodine deficiency, the prevalence of goiter is as high as 80%. [40]
While it's not a definitive rule, this general guideline can help you know when to look for signs you're eating too much. RELATED: 20 high-protein, low-calorie meals that are easy to make and ...
A relapsing encephalopathy occurs in association with autoimmune (Hashimoto's or Ord's thyroiditis), with high titers of antithyroid antibodies. Clinically, the condition may present one or more symptoms. Onset is often gradual and may go unnoticed by the patient and close associates to the patients.
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