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Part of creating a treatment strategy for migraine involves reducing and preventing central sensitization because when that kicks in, "it's harder to treat migraines and certain medications don't ...
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
CGRP antagonists can be used for both acute migraine treatment as well as prophylactically. [14] CGRP is a neuropeptide which is thought to induce migraines via vasodilation of cranial arteries. [14] CGRP can also release inflammatory agents and cause nervous system sensitization. [14]
Flunarizine is effective in the prophylaxis of migraine, [2] occlusive peripheral vascular disease, vertigo of central and peripheral origin, [3] and as an add-on in the treatment of epilepsy where its effect is weak and not recommended. [4] It has been shown to significantly reduce headache frequency and severity in both adults and children.
Migraines are characterized by severe head pain that pulses or throbs, often on one side of the head. Learn more about symptoms and signs of migraines, plus what causes migraines and how to get ...
Migraine impacts around 10% of people all over the world. It is important for people to have treatment options, and data like this review may help guide treatment recommendations in the future.
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