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Paroxetine, sold under the brand name Paxil among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [7] It is used to treat major depressive disorder, obsessive–compulsive disorder (OCD), panic disorder, social anxiety disorder, post-traumatic stress disorder (PTSD), generalized anxiety disorder, and premenstrual dysphoric disorder. [7]
Over two million prescriptions for paroxetine were written for children or adolescents in the US in 2002. [29]Funded by SmithKline Beecham, the acute phase of study 329 was an eight-week, double-blind, randomized clinical trial conducted in 12 university or hospital psychiatric departments in the United States and Canada between 1994 and 1997.
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Paroxetine isn’t supposed to be prescribed for children, although it can be prescribed for young adults. “In pooled analyses of placebo-controlled trials of antidepressant drugs (selective ...
Drugs known as antidepressants are often the first choice prescribed by healthcare professionals. And one of the most common types of antidepressants is SSRIs. ... Paroxetine (Paxil, Pexeva ...
Paroxetine (Paxil, Pexeva) ... If you’re prescribed escitalopram or any other type of antidepressant and experience a worsening of symptoms or an increase in thoughts of death, contact your ...
As demonstrated in table 2, paroxetine also inhibits the NOSs enzyme which could be the reason for its sexual dysfunction adverse effect, especially in men. [18] Paroxetine shows the highest affinity for muscarinic receptors of all the SSRIs which results in weak anticholinergic activity and therefore undesirable adverse effects.
Paroxetine CR was superior to placebo on the primary outcome measure. In a 10-week randomized controlled, double-blind trial escitalopram was more effective than placebo. [34] Fluvoxamine, another SSRI, has shown positive results. [35] However, evidence for their effectiveness and acceptability is unclear. [36]