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  2. List of best-selling video game franchises - Wikipedia

    en.wikipedia.org/wiki/List_of_best-selling_video...

    The Oregon Trail is a series of educational computer games that began with the first edition originally developed by Don Rawitsch, Bill Heinemann, and Paul Dillenberger in 1971 and produced by the Minnesota Educational Computing Consortium (MECC) in 1974. The original game was designed to teach school children about the realities of 19th ...

  3. SOD1 - Wikipedia

    en.wikipedia.org/wiki/SOD1

    SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.