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The side effects of bicalutamide, a nonsteroidal antiandrogen (NSAA), including its frequent and rare side effects, have been well-studied and characterized. The most common side effects of bicalutamide monotherapy in men include breast tenderness , breast growth , feminization , demasculinization , and hot flashes .
Serum sickness is a type III hypersensitivity reaction, caused by immune complexes. [2] When an antiserum is given, the human immune system can mistake the proteins present for harmful antigens . The body produces antibodies, which combine with these proteins to form immune complexes. [ 2 ]
Laboratory abnormalities include normal or mild decreases in serum C3, C4, and CH50 levels, and mild proteinuria. In contrast to true serum sickness, renal and hepatic involvement is rare. Significant decreases in serum C3, C4, and CH50, reported in the literature for true serum sickness, are rarely described in serum sickness–like reaction.
PACVs were first deployed to Vietnam in May 1966 as PACV Division 107, Task Force 116, where they were used by the Navy for riverine patrol missions in the Mekong Delta and on the Mekong River. [ 26 ] : 15 Often called "Pac Vees", they were armed with a .50 caliber machine gun mounted on a rotating platform in the front and two side-mounted M60 ...
The FDA said the recall of the device BioZorb Marker, initiated by Hologic in March, was not a product removal, but a correction. The agency also urged patients to report any side effects they ...
[85] [62] However, in contrast, the effects of the elevated estrogen levels remain unopposed by bicalutamide, and this is importantly involved in the feminizing side effects (e.g., gynecomastia) of the drug in men. [106] Testosterone levels decline with age in men and younger men have higher testosterone levels on average than older men. [107]
Others have admitted to falling victim to so-called “eyelash serum blindness,” meaning users were initially unaware of the side effects, like reddish rings and sunken eyes, that developed over ...
In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."