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Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...
The thyroid is found in the neck, and is responsible for producing hormones that in turn play a role in metabolism, growth and development in children, temperature regulation and in the ...
Other research indicates muscle fiber fatigue, weakness, and degradation associated with TM is the direct action thyroxine has on the muscle fibers themselves. Research suggests thyroxine directly causes a decrease in protein kinase affinity to cAMP within muscle fibers [ 1 ] [ 10 ] This causes an increase in cAMP within the muscle fibers since ...
TSH may be useful to detect poor thyroid output and may reflect the state of thyroid hormones in the hypothalamic-pituitary axis, but not the presence of hormones in other body tissues. [ 21 ] [ 74 ] [ 89 ] As a result, LT 4 monotherapy may not result in a "truly biochemically euthyroid state."
If there is a deficiency of dietary iodine, the thyroid will not be able to make thyroid hormones. [57] The lack of thyroid hormones will lead to decreased negative feedback on the pituitary, leading to increased production of thyroid-stimulating hormone , which causes the thyroid to enlarge (the resulting medical condition is called endemic ...
The pituitary gland secretes thyrotropin (TSH; Thyroid Stimulating Hormone) that stimulates the thyroid to secrete thyroxine (T4) and, to a lesser degree, triiodothyronine (T3). The major portion of T3, however, is produced in peripheral organs, e.g. liver, adipose tissue, glia and skeletal muscle by deiodination from
However, as the two thyroid hormones travel bound to other molecules, and it is the "free" component that is biologically active, free T 3 and free T 4 levels can be measured. [84] T 3 is preferred, because in hypothyroidism T 3 levels may be normal. [84] The ratio of bound to unbound thyroid hormones is known as the thyroid hormone binding ...
The hormone produced by the thyroid gland has big impact on bone density, blood calcium levee. [4] Abnormalities of the thyroid gland impact bone disease such as osteoporosis, a condition that is common in women but men can be diagnosed with this silent disease as well as it mainly affects elderly individual. [citation needed]
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