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Megalencephaly (or macrencephaly; abbreviated MEG) is a growth development disorder in which the brain is abnormally large. It is characterized by a brain with an average weight that is 2.5 standard deviations above the mean of the general population. [2]
Macrocephaly is a condition in which circumference of the human head is abnormally large. [1] It may be pathological or harmless, and can be a familial genetic characteristic. . People diagnosed with macrocephaly will receive further medical tests to determine whether the syndrome is accompanied by particular disorde
The diagnosis is made based on positive signs and symptoms in the history and examination during consultation of a neurologist. [ 3 ] Physiotherapy is particularly helpful for patients with motor symptoms (weakness, gait disorders, movement disorders) and tailored cognitive behavioural therapy has the best evidence in patients with non ...
Along with the brain, it develops from the dorsal nerve cord in the embryonic stage. The spinal cord consists of such segmental enlargements called ganglia. These ganglia form the basis for the peripheral nervous system’s (PNS) sensory and motor neurons that innervate various parts of the body.
This disease is characterized by loss of memory and intellectual function and by changes in mood. These changes encompass what are known as executive functions of the brain. [4] It usually presents between 54 and 66 years of age, and the first symptoms are usually mental deterioration or stroke. [5]
Lesions in the area of cerebellopontine angle cause signs and symptoms secondary to compression of nearby cranial nerves, including cranial nerve V (trigeminal), cranial nerve VII (facial), and cranial nerve VIII (vestibulocochlear). The most common cerebellopontine angle (CPA) tumor is a vestibular schwannoma affecting cranial nerve VIII (80% ...
The diagnosis of frontal lobe disorder can be divided into the following three categories: Clinical history Frontal lobe disorders may be recognized through a sudden and dramatic change in a person's personality , for example with loss of social awareness, disinhibition, emotional instability, irritability or impulsiveness.
A child with Sotos syndrome showing characteristic facial features Sotos syndrome in the hand, showing enlargement. This syndrome is characterized by overgrowth and advanced bone age. Affected individuals have dysmorphic features, with macrodolichocephaly, downslanting palpebral fissures and a pointed chin. The facial appearance is most notable ...
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