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2. Sirtuin 4 - Wikipedia

   en.wikipedia.org/wiki/Sirtuin_4

   SIRT4 is a mitochondrial ADP-ribosyltransferase that inhibits mitochondrial glutamate dehydrogenase 1 activity, thereby downregulating insulin secretion in response to amino acids. [7] A deacetylation of malonyl-CoA decarboxylase enzyme by SIRT4 represses the enzyme activity, inhibiting fatty acid oxidation in muscle and liver cells.

3. Glutamate dehydrogenase - Wikipedia

   en.wikipedia.org/wiki/Glutamate_dehydrogenase

   Beta cells secrete insulin in response to an increase in the ATP:ADP ratio, and, as amino acids are broken down by GLDH into α-ketoglutarate, this ratio rises and more insulin is secreted. SIRT4 is necessary to regulate the metabolism of amino acids as a method of controlling insulin secretion and regulating blood glucose levels.

4. Amatoxin - Wikipedia

   en.wikipedia.org/wiki/Amatoxin

   All amatoxins are cyclic peptides that are synthesized as 35-amino-acid proproteins, from which the final eight amino acids are cleaved by a prolyl oligopeptidase. [3] The schematic amino acid sequence of amatoxins is Ile-Trp-Gly-Ile-Gly-Cys-Asn-Pro with cross-linking between Trp and Cys via the sulfoxide (S=O) moiety and hydroxylation in ...

5. Proteolysis - Wikipedia

   en.wikipedia.org/wiki/Proteolysis

   A good example is the blood clotting cascade whereby an initial event triggers a cascade of sequential proteolytic activation of many specific proteases, resulting in blood coagulation. The complement system of the immune response also involves a complex sequential proteolytic activation and interaction that result in an attack on invading ...

6. Inborn errors of metabolism - Wikipedia

   en.wikipedia.org/wiki/Inborn_errors_of_metabolism

   Ferric chloride test (detects abnormal metabolites in urine) Ninhydrin paper chromatography (detects abnormal amino acid patterns) Guthrie test (detects excessive amounts of specific amino acids in blood) The dried blood spot can be used for multianalyte testing using Tandem Mass Spectrometry (MS/MS). This given an indication for a disorder.

7. AOL Mail for Verizon Customers - AOL Help

   help.aol.com/products/aol-mail-verizon

   AOL Mail welcomes Verizon customers to our safe and delightful email experience!

8. Serine - Wikipedia

   en.wikipedia.org/wiki/Serine

   Serine (symbol Ser or S) [3] [4] is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated − NH +3 form under biological conditions), a carboxyl group (which is in the deprotonated − COO −

9. AOL Mail

   mail.aol.com/?rp=webmail-std/en-us/basic

   Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!