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Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process. [5]
The latter can be demonstrated with special staining techniques (immunohistochemistry for cytokeratins) to identify the basal cells forming the supporting layer of the acinus. In prostate cancer, the abnormal cells spread beyond the boundaries of the acinus and form clusters without basal cells. In HGPIN, the basal cell layer is disrupted but ...
Over 98% of SGc occur in patients over the age of 40. [7] The mean age of diagnosis for periocular and extraocular SGc is around 67 years. Periocular SGc tends to be more common in women, while extraocular SGc tends to be more common in men. [2] SGc is extraordinarily rare in children with only a few cases reported. [6]
ASAP, generally, is not considered a pre-malignancy, or a carcinoma in situ; it is an expression of diagnostic uncertainty, [1] and analogous to the diagnosis of ASCUS (atypical squamous cells of undetermined significance) on the Pap test.
Acute myeloid leukemia (AML) is a cancer of the myeloid line of blood cells, characterized by the rapid growth of abnormal cells that build up in the bone marrow and blood and interfere with normal blood cell production. [1] Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. [1]
Urothelial cell cancers comprise just over half of primary urethral cancers. Roughly another quarter of cases are squamous cell carcinomas, and the majority of the remainder are adenocarcinomas, which originate from the cells of various secretory glands in and around the urethra. Up to 10% of primary urethral cancers have variant histology ...
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Ureter cancer rarely causes problems in the early stages, but as the cancer progresses, there are often side effects. [5] Symptoms of ureteral cancer may include "blood in the urine (); diminished urine stream and straining to void (caused by urethral stricture); frequent urination and increased nighttime urination (); hardening of tissue in the perineum, labia, or penis; itching; incontinence ...