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Nortriptyline is an active metabolite of amitriptyline by demethylation in the liver. Chemically, it is a secondary amine dibenzocycloheptene and pharmacologically it is classed as a first-generation antidepressant. [36] Nortriptyline may also have a sleep-improving effect due to antagonism of the H 1 and 5-HT 2A receptors. [37]
The trial's findings showed that while Prevagen seemed to improve users' brain health, as measured by various cognitive tests, over a period of 90 days, it didn't do any better than a typical ...
TikTok is filled with tips and tricks — some legitimate, many not — to help you sleep better.One of the latest encourages people to follow a 10-3-2-1-0 sleep rule, which is actually not just ...
Chlorpromazine, an antipsychotic and antiemetic drug which is classed as a "major" tranquilizer, may cause paradoxical effects such as agitation, hallucinations, excitement, insomnia, bizarre dreams, aggravation of psychotic symptoms and toxic confusional states. [8] These may be more common in elderly dementia patients.
The second-generation antidepressants are a class of antidepressants characterized primarily by the era of their introduction, approximately coinciding with the 1970s and 1980s, rather than by their chemical structure or by their pharmacological effect.
A new study reveals a shocking potential cause for insomnia.
Sleep state misperception (SSM) is a term in the International Classification of Sleep Disorders (ICSD) most commonly used for people who mistakenly perceive their sleep as wakefulness, [1] [2] though it has been proposed that it can be applied to those who severely overestimate their sleep time as well [3] ("positive" sleep state misperception). [4]
Here are links to possibly useful sources of information about Nortriptyline. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC